Aplastic Anemia
Educational information. Individual clinical review of this presentation by Dr. Ehsan is not yet documented. It does not replace personal medical evaluation.
Source: MedlinePlus, National Library of Medicine. Read the original source
MedlinePlus data edition September 26, 2026. Imported September 27, 2026. These dates do not indicate a new clinical review of the article.
What is aplastic anemia?
Aplastic anemia is a rare but serious blood disorder. If you have it, your bone marrow doesn't make enough new blood cells. It happens when there is damage to stem cells inside your bone marrow. There are different types of aplastic anemia, including Fanconi anemia.
What causes aplastic anemia?
The causes of aplastic anemia can include:
- Autoimmune disorders, which are the most common cause
- Certain inherited gene changes, such as the one that can cause Fanconi anemia
- Toxic substances, such as pesticides, arsenic, and benzene
- Radiation therapy and chemotherapy for cancer
- Certain medicines
- Viral infections such as hepatitis, Epstein-Barr virus, or HIV
- Pregnancy
In many people, the cause is unknown. This is called idiopathic aplastic anemia.
What are the symptoms of aplastic anemia?
Aplastic anemia can develop suddenly or slowly. It can be mild or severe. The symptoms of aplastic anemia can include:
- Fatigue
- Weakness
- Dizziness
- Shortness of breath
- Easy bruising or bleeding
What other problems can aplastic anemia cause?
Aplastic anemia can cause other problems, including frequent infections and bleeding. It raises your risk of developing a serious blood disorder.
If not treated, aplastic anemia can also lead to heart problems such as an arrhythmia (a problem with the rate or rhythm of your heartbeat), an enlarged heart, or heart failure.
How is aplastic anemia diagnosed?
To find out if you have aplastic anemia, your doctor will:
- Take your medical and your family medical histories
- Do a physical exam
- Order tests, such as tests to check if you have low numbers of cells in your bone marrow and blood
What are the treatments for aplastic anemia?
If you have aplastic anemia, your doctor will create a treatment plan for you. The plan will be based on how severe the anemia is and what is causing it. Treatments can include:
- Blood transfusions
- Blood and marrow stem cell transplants
- Medicines to suppress your immune system
Because of the risk of blood disorders, your doctor will monitor your condition and screen you for blood disorders regularly.
NIH: National Heart, Lung, and Blood Institute
Symptoms, tests and care options
Further reading selected by MedlinePlus. Links open the original organizations’ websites.
- Blood Tests · National Heart, Lung, and Blood Institute
- Complete Blood Count (CBC) · National Library of Medicine
- Iron Chelation · Aplastic Anemia and MDS International Foundation
- Reticulocyte Count · National Library of Medicine
- Treatments for Blood Disorders · National Heart, Lung, and Blood Institute
- What Are the Treatments for Aplastic Anemia? · Aplastic Anemia and MDS International Foundation
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